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| Tchaou,Blaise Adelin; Tové,Kofi-Mensa Savi de; Tové,Yolande Sissinto-Savi de; Djomga,Aurélien Tchémaha C.; Aguemon,Abdou-Rahman; Massougbodji,Achille; Chippaux,Jean-Philippe. |
| Abstract Background In Africa, snakebite envenomations are frequently complicated by life-threatening hemorrhagic syndromes. The authors of the present study conducted a prospective analysis at the University Hospital of Parakou (north of Benin) for seven months (January 1 to July 31, 2014) to assess the contribution of ultrasonography to the diagnosis of internal bleedings and management of envenomation. Methods An ultrasound examination was performed in all patients with clinical envenomation regardless of its severity. The study involved 32 patients admitted to the ICU of the University Hospital of Parakou. Results The average age was 27 ± 13.9 years. The main signs of severity were: prolongation of clotting time (88 %), severe anemia (41 %),... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Envenomation; Ultrasound; Internal bleeding; Hemoperitoneum; Hematoma. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992016000100306 |
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| Chippaux,Jean-Philippe; Akaffou,Marc Hermann; Allali,Bernard Kouadio; Dosso,Mireille; Massougbodji,Achille; Barraviera,Benedito. |
| Abstract During the 6th International Conference on Envenomation by Snakebites and Scorpion Stings in Africa held in Abidjan, from 1 to 5 June 2015, the measures for the management of envenomation were discussed and new recommendations were adopted by the participants. The high incidence and severity of this affliction were confirmed by several studies conducted in African countries. The poor availability of antivenom, particularly because of the cost, was also highlighted. Some experiences have been reported, mainly those regarding the financial support of antivenom in Burkina Faso (more than 90 %) and Togo (up to 60 %) or the mandatory reporting of cases in Cameroon. Key recommendations concerned: improvement of epidemiological information based on case... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Envenomation; Antivenom; Epidemiology; Drug policy; Africa. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992016000100101 |
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| Chippaux,Jean-Philippe; Massougbodji,Achille; Habib,Abdulrazaq G.. |
| Abstract Snakebite is a critical public health issue in tropical countries, particularly in Africa, where 20% of snakebites globally occur. In 2017, the WHO added snakebite envenoming to the category A of neglected tropical diseases. In 2019, thanks to broad institutional and international NGO support, including strong mobilization of African experts and governments, WHO launched a strategy for prevention and control of snakebite envenoming with more ambitious goals. In sub-Saharan Africa, accessibility of antivenoms and symptomatic, adjuvant or replacement therapy is a priority. Several antivenoms are available but their evaluation has not been properly carried out and they remain expensive. To date, there are no manufacturers of antivenom in sub-Saharan... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Snakebite; Envenomation; Antivenom; Sub-Saharan Africa; Neglected tropical diseases; Control. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100101 |
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| Baldé,Mamadou C; Chippaux,Jean-Philippe; Boiro,Mamadou Y; Stock,Roberto P; Massougbodji,Achille. |
| Background In Guinea Elapids are responsible for 20% of envenomations. The associated case fatality rate (CFR) ranged 15-27%, irrespective of treatment. Results We studied 77 neurotoxic envenomations divided in 3 groups: a set of patients that received only traditional or symptomatic treatments, and two other groups that received either 2 or 4 initial vials of Antivipmyn® Africa renewed as necessary. CFR was 27.3%, 15.4% and 17.6%, respectively. Although antivenom treatment was likely to reduce CFR, it didn’t seem to have an obvious clinical benefit for the patients, suggesting a low treatment efficacy. Mean delay to treatment or clinical stages were not significantly different between the patients who recovered and the patients who died, or between... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Elapid; Neurotoxins; Treatment; Antivenom; Guinea; Africa. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992013000100304 |
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